What are the symptoms of hereditary nephritis?
1, hearing impairment
Alpert syndrome in patients with hearing loss manifested as sensorineural deafness, occurred in the cochlear area. Deafness for the progressive, bilateral is not completely symmetrical, early for high-frequency hearing loss, to be used to monitor the hearing meter, gradually and full range, and even affect the daily dialogue and exchange. At present, there is no report of congenital deafness. X-linked dominant genotype Alport syndrome male incidence of deafness than women, the occurrence of older than women earlier
2, kidney performance
Hematuria to the most common, mostly glomerular hematuria, X-linked dominant genotype Alport syndrome in patients with male proteinuria, with age or hematuria and the performance of persistent proteinuria, and even nephrotic range of proteinuria. The first hospital in Peking University reported the level of proteinuria in nephrotic syndrome, and suggested poor prognosis. Similarly, the incidence and severity of hypertension also increased with age, and occurred in male patients.
3, eye lesions
Alport syndrome characteristic ocular lesions include the former conical lens, fundus macular spot around the spot and spotted retinopathy and retinal equatorial retinopathy. The anterior conical lens appears as the central part of the lens protruding to the anterior capsule, the patient can be expressed as progressive myopia, and even lead to pre-polar cataract or spontaneous perforation of the anterior capsule. At present, there have been no reports of autosomal dominant Alport syndrome in patients with ocular involvement.
4, abnormal blood system
At present, AMME syndrome is associated with abnormal blood system Alport syndrome, mainly for the Alport, mental retardation, facial dysplasia and oval polycythemia. Studies have confirmed that this Alport syndrome COL4A5 gene is completely deleted, and the gene deletion beyond the 3 'end. In addition, previously reported abnormalities in the blood system, such as giant platelets, platelet abnormalities associated with leukocyte inclusion bodies and only platelet abnormalities, accompanied by "Alport-like" manifestations, have been shown to be non-myosin heavy chain 9 genes MYH9 mutations are caused by mutations in the type IV collagen gene. Therefore, such diseases are not Alport syndrome, known as MYH11A syndrome, for autosomal dominant inheritance.
5, diffuse leiomyoma
Some adolescent Alport syndrome families or patients with significant smooth muscle hypertrophy, esophagus, trachea and female genital tract (such as the clitoris, labia minora and uterus, etc.) for the most common parts of the affected, and the corresponding symptoms, such as dysphagia and breathing Difficulty and so on.
First, control the diet
To avoid excessive intake of acidic substances, aggravate the acidic body. Diet acid and alkali balance for the treatment of diabetes and the prevention and treatment of complications is a very important part. Diet to eat more organic plants rich in organic foods, eat less meat, eat more vegetables.
Second, to participate in aerobic exercise
Appropriate exercise, exercise in the sun more sweating, can help remove the body of excess acidic substances, so as to prevent the occurrence of kidney disease.
Third, keep a good mood
Do not have too much psychological pressure, excessive pressure will lead to the deposition of acidic substances, affecting the normal metabolism. Appropriate to adjust the mood and their own pressure can maintain a weak alkaline body, so as to prevent the occurrence of kidney disease.
Fourth, life to the law
Life habits of irregular people, such as the night to sing karaoke OK, playing mahjong, night home and other life without law, will increase the physical acidification.
Fifth, away from the smoke, wine
Smoke, wine is a typical acidic food, unrestrained smoking and drinking, can easily lead to the body's acidification, making kidney disease can take advantage. In daily life to drink tea in addition to the prevention and improvement of treatment of nephritis can also regulate the balance of human body, anti-inflammatory antibacterial, detoxification, enhance human resistance. This kind of Chinese herbal tea mainly honeysuckle, wild chrysanthemum, Cordyceps and so on.
Sixth, do not eat contaminated food
Such as contaminated water, crops, poultry eggs, etc., to eat some green organic food, to prevent the disease from the mouth.
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