2017年11月24日星期五

Do You Use Immunosuppressants Correctly For Kidney Disease

Do You Use Immunosuppressants CorrectlyImmunosuppressants are commonly used for kidney disease. But do you use them correctly? Follow us to see the details.
If steroids do not work for Nephrotic Syndrome, immunosuppressants will be used. There are various immunosuppressants including cyclophosphamide, ciclosporin, Cellcept, azathioprine, tacrolimus and Leflunomide, etc.


Memerous Nephropathy
Patients with Memerous Nephropathy can take cyclophosphamide, tacrolimus, Cellcept and ciclosporin.
Minimal Change Disease (MCD)

Patients with MCD can take Cellcept and Ciclosporin. Generally they just need to take steroids. If you worry about the side effects from steroids, you can take immunosuppressants.
If economic conditions permit or young people need to get pregnancy, they can take Cellcept or ciclosporin.

Focal Segmental Glomerulonephritis (FSGS)
Patients with FSGS can take Ciclosporin and Cyclophosphamide. In general, FSGS is treated by steroids and Cyclophosphamide. If you are afraid that Cyclophosphamide is useless or has gonad toxicity, you can take Ciclosporin.
Lupus Nephritis and ANCA related small vessel vasculitis

Correct immunosuppressants include Cyclophosphamide, azathioprine, Cellcept and Tacrolimus. If your condition is not relieved, you can take steroids and Cyclophosphamide together. You can also take Tacrolimus. When your condition is stable, you can take azathioprine.

Leflunomide can be used for lupus nephritis, IgA Nephropathy and FSGS.
Tripterygium glycosides is effective for purpura nephritis and glomerulonephritis. However, due to liver toxicity, gonad toxicity and decreased white blood cells, it is replaced gradually by Sartan drugs and Pril drugs.
Immunosuppressants should be used in a small dosage for a long time. Large dosage will cause serious side effects.

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